Certified Registered Nurse Anesthetist (CRNA) Practice Exam

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What is the normal cerebral perfusion pressure (CPP) range?

50-70 mmHg
60-100 mmHg
80-120 mmHg
70-90 mmHg

The correct answer is: 60-100 mmHg

The normal cerebral perfusion pressure (CPP) range is considered to be between 60-100 mmHg. This range is crucial for maintaining adequate blood flow to the brain, which is essential for normal neurological function. CPP is calculated using the formula: CPP = Mean Arterial Pressure (MAP) - Intracranial Pressure (ICP). A CPP value within this range ensures that the brain receives sufficient oxygen and nutrients while removing metabolic wastes. If the CPP falls below 60 mmHg, it may indicate inadequate perfusion, leading to potential ischemia and damage to brain tissue. Conversely, values significantly above 100 mmHg can indicate hyperperfusion, which may also have detrimental effects. The range 60-100 mmHg is considered optimal for preventing both ischemic and hyperperfusion injuries, supporting optimal cerebral metabolism and function. Understanding this range is fundamental for healthcare professionals, especially those working in critical care and anesthesia, as they must assess and manage the perfusion needs of their patients effectively.