Certified Registered Nurse Anesthetist (CRNA) Practice Exam

What is the recommended dose of Clonidine for hypertension management?

1. 0.05-0.1 mg

2. 0.1-0.2 mg

3. 0.2-0.3 mg

4. 0.4-0.5 mg

The correct answer is: 0.1-0.2 mg

The recommended dose of Clonidine for hypertension management typically ranges from 0.1 to 0.2 mg, making this answer accurate. Clonidine is an alpha-2 adrenergic agonist that effectively lowers blood pressure by decreasing sympathetic outflow from the central nervous system. This reduction in sympathetic activity leads to decreased heart rate and vascular resistance, which ultimately assists in managing hypertension. Starting doses often begin at 0.1 mg, with titrations made based on the patient's response and tolerance. The upper limit of this dosing range (0.2 mg) is used for patients who need additional control over their blood pressure, reflecting common clinical practice as recommended in hypertension management guidelines. Proper dosage is essential, as higher doses can lead to increased side effects, including sedation and dry mouth, which might adversely affect patient compliance. Therefore, selecting a dose within the recommended range is crucial for achieving the desired therapeutic effect while minimizing the risk of side effects.